Chemotherapy (anti-cancer medication) is one of the main treatments for Hodgkin disease. It may be given on its own or in combination with radiotherapy. Chemo destroys the lymphoma cells by disrupting their growth.
how is it given?
The drugs can reach anywhere in the body via the bloodstream. It is given by injection or infusion (drip) into a vein (intravenously). This is usually through a central line or a PICC line - find out more.
A combination of a few drugs is given over a period of days followed by a gap of a few weeks. This is known as a cycle of treatment. During the gap inbetween treatment your body (and blood cells) have time to recover from any side effects before the next lot of treatment is given. Your whole treatment will probably last for several months in total. Usually it’s given as an outpatient, but sometimes you might have to stay in hospital for a few days.
which drugs will I have?
Your specialist will plan the best treatment for your situation but there are some combinations of chemo that are commonly used for Hodgkin disease. One of the most commonly used combinations or regimens is doxorubicin (trade name adriamycin), bleomycin, vinblastine and dacarbazine or ABVD. This is usually given as a day patient.
are there any side effects?
Different chemo drugs cause different side effects. Some people just have a few side effects and others have more. It's hard to predict how it's going to be for you as everyone is different and reactions can vary from treatment to treatment.
Almost all side effects are short term and will gradually disappear once treatment stops. The most common side effects are hair loss, tiredness, sickness (which can be controlled) and a lowered immune system (which means you pick up infections more easily). Treatment can affect fertility, and for girls, their periods may be affected. You may also feel low in mood. If you want to know more about the regimen and side effects of chemotherapy, there is lots more information in the chemotherapy section and the deal with it section.
